The Cosgrove Group at Keele University
Using continuous flow biocatalysis to enable enzymes for organic synthesis
Biocatalysis
Continuous Flow
Bioprocess optimisation
We are a research group at Keele University in the UK. Our research focusses on using technology to improve and increase biocatalysis application in synthetic chemistry, with a particular focus on enzyme immobilisation and continuous flow.
Group news
09/2024: Welcome to the group several new colleagues: Andrea is re-joining for her PhD, and Jana is a new PhD student! Aimee, Alistair and Joey are also joining the group as masters students for this academic year. Welcome all!
09/2024: A collaborative paper with Prof Nick Turner is out in ACS Catalysis. The multifunctionality of IREDs is further demonstrated with multiple reactions demonstrated in a single pot. See the work here.
08/2024: The final paper from Alice’s project is out in Organic Letters now! A nice one-pot alcohol oxidase-Wittig reaction entirely in water. With Liam as well, the first paper of his PhD! Well done both!
06/2024: Two new papers out from the group this month! One from the groups first MChem Lauren, showing how nitroreductase can be used for fragment generation. The second is a perspective, written with colleague Becky Ruscoe, about flow biocatalysis and the impact of technology in recent years. Check them out!
06/2024: Tom and Chris were both awarded prizes at the Keele and Manchester PGR conferences for their oral and poster presentations, respectively. Well done both!
06/2024: Seb presented the groups work at the Go With The Flow conference in Cardiff, and then at the University of Manchester.
06/2024: Alberto joined the group as a PDRA on the BBSRC prosperity partnership with Unilever.
05/2024: Tom presented his work at NextGenBiocat in Crete.
02/2024: There is a postdoctoral research associate position available with us and Prof Gavin Miller. The project is a collaboration with Unilever, UCL, the University of Manchester and the University of Liverpool, funded by the BBSRC.
02/2024: We have a new PhD studentship available for a 09/2024 start. The project, which will focus on enzymatic approaches to surfactant-like molecules and derivatives, is in collaboration with Prof Gavin Miller and industry partners Unilever.
12/2023: Alice passed her viva!!! Well done Dr Wahart, the first PhD student of the Cosgrove group! Thanks very much to Prof Nick Turner and Dr Mark Skidmore for examining. Keep in touch Alice!
11/2023: We have a new PhD studentship available for a 09/2024 start. The project, which will focus on the development of glycoconjugate synthesis in continuous flow, is in collaboration with Prof Gavin Miller and industry partners Iceni Glycoscience.
10/2023: Well done to Alice and Simon who have published our new article in ChemBioChem looking at using alcohol oxidases for bioremediation!
10/2023: We have a new website!
09/2023: Welcome to the group Apisit who has started his PhD with us, and Andrea and Matthew who will both work for the next year with us as Masters students.
Dr Sebastian Cosgrove
Get in touch
s.cosgrove@keele.ac.uk
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